I know I just did a blog post about diabetes management technology, but this new device in the works is much cooler and more advanced. It's called the closed-loop system, or the "bionic pancreas". Before I go more into detail about what it is or how it works, you need some background information about type 1 diabetes management in order to fully understand how cool this device is. Diabetics' pancreases no longer produce insulin or regulate blood glucose levels so we are required to do the work of our pancreases. This includes checking our blood glucose levels via finger prick about 6 times a day, counting how many carbs are in a meal, entering the number into an insulin pump and taking the dosage, or manually calculating the amount of insulin needed and giving it via injection. In addition, if our blood sugar levels are too low we need to eat sugar, or if they are too high, we need to give more insulin. It requires constant thought and management.
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| Some technology that diabetics can currently use to manage blood glucose levels |
That's why the bionic pancreas is so exciting to diabetics everywhere, it does all the thinking and calculating for you! Now onto how it works and how it relates to computer science. The basic closed loop system has three parts: a continuous glucose monitoring system (CGM), a device that can run the complex algorithm, and a special kind of insulin pump. The CGM is attached to the body takes a reading of interstitial fluid. It converts this reading to a measure of blood glucose and sends it to the device that runs the algorithm. The algorithm is extremely complicated and has been in the works for about 10 years now. It computes the proper treatment to give the user based on their blood sugar. Not only does it learn to treat each person's blood sugars differently, but it also takes into account other factors that can affect blood sugar like meals, exercise, illness, hormones, and emotions. The calculations are sent to the pump, and either insulin or glucagon (a hormone that raises blood sugar) are delivered via a small wire in the body. Computer science is crucial to this system because if the dosages are wrong, the results could be extremely serious, even fatal. The algorithm needs to be so precise in order to work properly.
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| An early version of the bionic pancreas |
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The most recent prototype of the system. Not pictured: the CGM, a small
patch worn on the skin. The numbers will be sent to the pictured device |
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(Some more information from personal experience, if you're interested)
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| Two of my friends who participated in the bionic pancreas camp study! |
I'm not going to talk much more about comp sci here, but if you're interested in medicine or this technology, then keep reading! :) I work at a summer camp for type 1 diabetics and for two years (2013 and 2014) they tested the bionic pancreas system! It was so cool to see it in action and how well it works. My friend, Grace, was one of the patients in the trial and her HbA1c (a measure of average blood sugars over time) was perfect which is nearly impossible to achieve with the current technology. The inventor, Ed Damiano, hopes to get the technology approved by 2017 when his diabetic son goes to college. It is looking like it might take a little longer, but approval is on the horizon. After doing all the work for one of my organs for the past 15 years, it would be so amazing to finally have this technology and not need to worry about managing my blood glucose levels. Here's a cool video they made at my summer camp when they first tested it there!
https://www.youtube.com/watch?v=06rpdVs0okE
(sorry this blog post was excessively long, I'm just really excited about this)
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http://sixuntilme.com/wp/2015/11/06/bionic-pancreas-update-call-action/
http://helmsleytrust.org/programs/health-type-1-diabetes/case-studies
https://t1dexchange.org/pages/study-reveals-poor-disease-control-among-adolescents-and-young-adults-with-type-1-diabetes/
https://wefunder.com/betabionics/